Conference Title

Location

Day Month Year

Cell Symposia: Metabolism & Aging
March 27-29, 2011, Cape Cod, Massachusetts, USA

Conference Organisers

Speakers Domenico Accilli, USA Adam Antebi, Germany Dongsheng Cai, USA Hassy Cohen, USA Jill Crandall, USA Rafael de Cabo, USA Andy Dillin, USA David J. Glass, USA Leonard Guarente,USA Pankaj Kapahi, USA Brian Kennedy, USA James Kirkland, USA Valter D. Longo, USA Jim Nelson, USA Eric Ravussin, USA Randy Strong, USA Marc Tatar, USA Heidi Tissenbaum, USA Eric Verdin, USA

Prof. David A. Sinclair, Harvard Medical School, Boston, USA
Dr. Nir Barzilai, M.D., Albert Einstein College of Medicine, New York, USA
Dr. C. Ronald Kahn, Joslin Diabetes Center at Harvard Medical School, Boston, USA

For many decades, aging and metabolism were considered largely separate fields.

However, many of the most important discoveries are now occurring at the interface between the two. Interventions including caloric restriction, modulation in insulin and insulin like growth factor 1 (IGF-1), the sirtuin (sirt1) activator resveratrol, and the mammalian target of rapamycin (mTOR) have emerged as “protective” against the metabolic decline of aging, and have been shown to increase life span of several mammalian species. Elucidating how these pathways are interconnected and how they might be safely modulated to treat disease are among the most important challenges facing researchers in the coming decade.

This meeting aims to bring together scientists with interests in aging and metabolism to further explore how these fields intersect and to identify the most promising future directions. We will hear the latest data from leaders in the field about the key pathways at the level of the cell and the organ, across a range of contexts including model organisms, mammalian systems, and translational studies in primates and humans. Topics will also include how the signaling networks of metabolism and aging connect and communicate and how we can best make use of these connections to improve medicine and society.

Topic List

• Physiology & aging
• Aging from model organisms to humans
• Cell stress & organelle changes during aging
• Nutritional status and healthspan